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可复用性报告:多组学网络推断的稳健性取决于先验知识与数据可得性

Reusability report: multi-sample omics network inference operates in distinct robustness regimes defined by prior knowledge and data availability

摘要

Nature Machine Intelligence 发表的可复用性报告考察了此前提出的生物网络学习框架 CORNETO 的可复用性,发现稳健的网络推断取决于数据可得性、先验知识、正则化和生物学背景,并据此划分出不同的稳健性区间。原文链接:https://www.nature.com/articles/s42256-026-01311-y

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Nature Machine Intelligence, Published online: 19 October 2026; doi:10.1038/s42256-026-01311-y

This work studies the reusability of CORNETO, a previously developed framework for learning biological networks from multi-omics data. Robust network inference is found to depend on data availability, prior knowledge, regularization and biological context.


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来源:Nature Machine Intelligence · nature.com

引用原文

Xabier Martínez-de-Morentin. Reusability report: multi-sample omics network inference operates in distinct robustness regimes defined by prior knowledge and data availability[EB/OL]. (2026-10-19)[访问日期]. https://www.nature.com/articles/s42256-026-01311-y.